Biomolecular dynamics can be filmed in fantastic high-speed atomic force microscopy experiments. However, the interpretation of measurement results is often difficult due to limitations in the experimental spatio-temporal resolution. On the other side, the wealth of available protein structures is enormous. Molecular movies of functional conformational dynamics in proteins can furthermore be readily obtained from multi-scale molecular modeling.

The BioAFMviewer provides a stand-alone, versatile, and user-friendly software platform to transform structural and dynamical protein data into simulated AFM graphics that can be correlated with experimental images. We hope that BioAFMviewer applications help experimentalists in the interpretation of their observations.

Features:

- High-quality molecular viewer of PDB data
- Ultra-fast GPU accelerated computation of simulated AFM
- Automatized fitting to experimental AFM images
- Simulation AFM experiments from molecular movies
- Topography analysis toolbox
- Sample-substrate electrostatic predictions